Cctv newsAccording to the latest statistics of the National Cancer Center, the first malignant tumor death in China is lung cancer, with about 626,000 deaths per year, followed by liver cancer, stomach cancer and esophageal cancer. Esophageal cancer ranks the fourth among the causes of death of malignant tumors in China. China is one of the regions with high incidence of esophageal cancer in the world. The onset age is mostly over 40 years old, mainly male.

　　　　　　 Statistics show that esophageal cancer ranks fourth among the causes of death of malignant tumors in China. There are 572,000 cases of esophageal cancer and 508,000 deaths worldwide every year. There are 307,000 cases of esophageal cancer and 283,000 deaths in China every year. The incidence and death of esophageal cancer in China account for about half of the world.

　　　　　　 He Jie, Dean of Cancer Hospital of China Academy of Medical Sciences, said that the typical symptoms of esophageal cancer are progressive dysphagia. First, it is difficult to swallow dry food, then semi-liquid food, and finally water and saliva can’t be swallowed. Its throat discomfort is mainly dryness, itching and burning sensation.

　　　　　　 Patients with high genetic risk of esophageal cancer have regular gastroscopy.

　　　　　　 Experts emphasize that esophageal cancer has certain heredity. The incidence of esophageal cancer often shows the phenomenon of familial aggregation, and many people with paternal positive family history, middle-aged and elderly people, patients with chronic esophagitis, people with family history of esophageal cancer, long-term bad eating habits, frequent smoking and drinking, and people who often eat pickled and smoked food are all high-risk groups of esophageal cancer.

　　　　　　 He Jie said that high-risk groups should have regular gastroscopy, usually once a year.

　　　　　　 Early intervention of esophageal cancer has high cure rate and survival rate.

　　　　　　 Experts point out that the cure rate and survival rate of esophageal cancer are quite high in early intervention treatment. At present, iodine staining of gastroscope is the standard scheme for screening and early diagnosis of esophageal cancer. Early esophageal cancer can survive for a long time and have a high quality of life after endoscopic resection. In life, everyone should pay attention to not eating hot food, eating less pickled food, moldy food and other foods with high nitrite content, not drinking spirits, quitting smoking and so on.

A few days ago, some netizens photographed the spy photos of a large SUV owned by AITO Wenjie. It is speculated that the car may be the M8 of Wenjie, and the car will be officially unveiled at the end of this year. Earlier, it was reported that the nine-seater M9 would launch a five-seater model, and the vehicle in the spy photos might also be the five-seater M9.

　　Looking at spy photos, the overall shape of the new car is basically the same as that of the M9, and it also adopts the shape, size and design of large SUVs. The M9′ s iconic through taillight and plump and rounded tail shape have been continued, and the roof and rear enclosure are covered with camouflage materials. It is still uncertain whether a new shape will be adopted.

　　In terms of power and configuration, its overall price is definitely lower than that of the M9 model, which is essential for Huawei’s driver assistance system and related intelligent configuration, and may not be as rich as the M9 model in terms of comfort configuration. We will continue to pay attention to more news about the new car. (Source: Ju Electrician Society)

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　　[car home Comparative Test] In the long river of history, the sigh of He Shengliang, who was born in Yu, has been endlessly repeated, and this subtle "CP" combination often brings changes to the world again and again. In the automobile circle, Toyota and Honda are such a pair of old enemies. Their competition with similar personalities has never stopped, but this continuous confrontation has also enabled the two companies to move forward together.

　　Many people say this about them: Honda is a technology house and Toyota is a businessman, but they are both Japanese brands, and their leather is durable, fuel-saving and environmental protection have become their common advantages. In the field of hybrid power, these two brands have also reached the top in the world, among which Honda (|) and Toyota Willanda (hereinafter referred to as CR-V and Willanda) seem to be one of the works that can best represent their hybrid power level at present. Today, we invite them together for a performance.

● Appearance contrast

　　After the change, the appearance of CR-V is not related to the old model, and the changes mainly focus on the style of front and rear enclosure and the material of body panel. Needless to say, Willanda, as the first compact SUV of GAC Toyota, has a brand-new appearance. Although it is somewhat similar to RAV4 Rongfang in overall outline, it is quite different in details.

　　The front faces of the two cars are all coquettish, and CR-V still continues the style of calm home, with a strong sense of tolerance. After the change, it enhances the sense of luxury through changes in details; The front face of the new Willanda adopts a more three-dimensional style, especially the fog lights and the front grille area, which is very prominent and looks younger and avant-garde than CR-V.

　　In fact, these two cars have gone in completely different directions in appearance design. Toyota Willanda tends to be young and wild, while Honda CR-V pays more attention to luxury and stability. In fact, we can see their differences only from the material of decorative parts. So much about the appearance. It is up to you to decide who is better in this part. Next, let’s take a look at the interior.

　　Commenting on Beckham’s sexy underwear poster, the spice girl said surprisingly, "I am very proud to see his 25-foot penis." If I look like this, I will walk in the street wearing only underwear … "

　　

　　　　Beckham’s big underwear advertisement landed in Milan

　　

　　　　Spice Girl: I’m proud of the size of his penis.

　　Netease Sports News: What is David Beckham most afraid of seeing? It is not the flying boots of former coach Ferguson, nor Capello’s indifference, or McClaren’s cruelty. The scene he is most afraid of seeing may be an interview with his wife Victoria. "Spice Girl" must have amazing words in every interview with Beckham. She once revealed that she called Beckham "Goldenballs", and this time, when commenting on Beckham’s underwear poster, Victoria brought another farce …

　　During Robert cavalli’s fashion show this week, Beckham’s advertisement for sexy underwear for Armani Company landed in Milan. On the huge billboard in Milan, people can see the "heartthrob" with open thighs and straight underwear. When asked what she thought of her husband’s advertising photo, the spice girl said, "I’m glad to see that his penis is 25 feet tall, which is great." ("I‘m proud to see his PENIS 25 foot tall. It‘s great.")

　　"This is huge, huge and burly." The spice girl continued, "If I could look like this, I would just walk in the street in my underwear."

Editor: Shuo Yang

On January 10th, the 2019 National Science and Technology Awards Conference was held in the Great Hall of the People. A total of seven first-completed unit achievements of Shanghai Jiaotong University were commended by the CPC Central Committee and the State Council, including one national special prize for scientific and technological progress, and the first one was Tan Jiahua; Two second prizes of national natural science, the first to be completed by Jia Jinfeng and Shi Yongyong; There is one second prize of national technological invention, the first person to complete it is Allergy, and there are three second prizes of national scientific and technological progress. The first people to complete it are Chen Daijie, Zhang Chenping and Fang Binghua respectively.

In 2019, our school won the National Science and Technology Award as the first completed unit;

1. Independent research and development and industrialization of large-scale cutter suction dredging equipment at sea.

The project was completed by Professor Tan Jiahua from the School of Ship, Ocean and Architecture Engineering, and won the national special prize for scientific and technological progress.

There is a huge demand for dredging in China, and dredgers used to rely on imports for a long time. Tan Jiahua led the project team to design more than 60 large-scale cutter suction dredgers, with an annual dredging volume of over 1 billion cubic meters and an annual output value of over 10 billion RMB. These cutter suction dredgers have become the main force in China’s dredging industry. They have created world-renowned China speed and many world records in the Belt and Road port construction, infrastructure construction, waterway dredging and other projects, created remarkable social and economic benefits, and played an irreplaceable role in building a maritime power, safeguarding national sovereignty and promoting national strategy.

2. Experimental study on preparation and quantum properties of topological quantum materials.

The project was completed by Professor Jia Jinfeng from the School of Physics and Astronomy, and won the second prize of National Natural Science.

In this project, an experimental method of realizing two-dimensional topological superconductors by using superconducting neighbor effect is proposed, and a three-dimensional topological insulator/superconductor heterojunction with an atomic level flat interface is prepared for the first time in the world, which proves that the system is a two-dimensional topological superconductor, and the conclusive evidence of the existence of majorana zero-energy mode is observed, which has been repeated and further confirmed by many international research groups. It lays a foundation for exploring topological quantum computing. Tin olefin thin films were prepared for the first time in the world, which opened the door for tin olefin experimental research. This work has aroused great academic repercussions in the world and has become a hot research direction.

3. Fine mapping of key genes of mental illness based on linkage disequilibrium and long haplotype analysis.

This project was completed by Professor Yong Yong from Bio-X Institute of College of Life Science and Technology, and won the second prize of National Natural Science.

Aiming at the difficulties and bottlenecks in the field of molecular genetics of complex traits, this project has innovated the theory and research methods of linkage disequilibrium analysis and long haplotype analysis of genome big data, and made a breakthrough in the molecular genetics research of mental diseases. The results of the project lay a foundation for accurate diagnosis and treatment of mental illness, and provided systematic research methods and experimental means for the study of genetic mechanism of complex diseases. Eight representative papers were published in the first-class journals in the field of molecular genetics, and SCI cited 1804 times, of which the highest citation was 1350 times for a single paper, and two invention patents were granted, which had high scientific innovation and application prospects.

4. Key technologies and systems of cloud computing for abrupt peak service.

This project was completed by Professor Allergy of School of Electronic Information and Electrical Engineering, and won the second prize of national technological invention.

This project belongs to the field of computer software, and mainly studies the problem of building a cloud computing system with strong real-time, high throughput, fast expansion and high robustness. Invented the rapid processing technology of sudden peak user requests, the high reliability and high throughput technology of data based on storage array optimization, the efficient resource integration technology based on container and mixed deployment, and the service quality assurance technology based on memory data analysis. The results of the project have been applied to more than 30 leading enterprises and institutions in the industry, which has replaced the foreign products of cloud computing basic software and effectively promoted the localization of core software.

5. Green and efficient key technological innovation and industrialization of the co-production of etimicin and gentamicin.

The project was completed by Professor Chen Daijie from the College of Pharmacy and won the second prize of National Science and Technology Progress Award.

This project belongs to microbial medicine technology in the field of biomedicine. The idea of "collinear co-production of antibiotics" was put forward for the first time, and the co-production process of etimicin and gentamicin was innovated with gentamicin C1a as the link. The precise feeding process with multi-parameter linkage control, high purity C1a and active blending purification process were established. And innovated the synthesis and purification process of etimicin, broke through the key technology of quality analysis and control of etimicin, and the established new method was included in the 2015 edition of Pharmacopoeia. The implementation of the project has greatly improved the yield and quality of products, and reduced the manufacturing cost and the discharge of three wastes.

6. Technical innovation and popularization of functional reconstruction of jaw defect.

The project was completed by Professor Zhang Chenping from the Ninth People’s Hospital affiliated to Medical College and won the second prize of National Science and Technology Progress Award.

Aiming at the worldwide problem of functional reconstruction of jaw defect, this project has established a complete technical system of functional reconstruction of jaw through more than 20 years of scientific research and technological innovation, and achieved a series of innovative results. The project team pioneered the "four-stage" mandibular reconstruction strategy, which solved the clinical problem of functional reconstruction of large dislocation jaw defect; The technique of vascularized fibula widening traction implantation was pioneered, which creatively integrated microsurgery, distraction osteogenesis and dental implantation, and achieved a major breakthrough in jaw reconstruction from "morphological repair" to "functional reconstruction". Through the international oral and maxillofacial surgery training base, national-level classes, international and domestic conferences and other technical promotion and professional personnel training, more than 10,000 patients benefited, and China’s leading position in the field of jaw reconstruction was established, making oral and maxillofacial surgery in China reach the international leading level.

7, "Emergency Room Story" medical popular science documentary

The project was completed by Professor Fang Binghua from the Sixth People’s Hospital and won the second prize of National Science and Technology Progress Award.

At present, there are two major topics in China’s medical and health undertakings: one is how to meet the people’s growing medical and health needs, realize the move forward of the pass, and raise the public’s awareness of disease prevention and treatment; The other is the contradiction between doctors and patients. Because of the asymmetry of information, both doctors and patients have incomplete understanding and unrealistic requirements for each other, which leads to conflicts. The Story of the Emergency Room explains these two problems in a documentary way. The panorama of the program shows the real hospital and medical process, and even many medical rescue routines that we usually don’t pay attention to, such as how to call an ambulance, what diseases should be seen in the emergency room, etc., and makes a good science popularization from all angles of medical care, seeking medical advice and mutual trust between doctors and patients. In addition, hundreds of millions of viewers on TV and the Internet, and non-didactic story-telling communication methods have created a peak in the arrival rate of popular science. Compared with traditional science popularization, it is a revolutionary innovation and breakthrough of medical science popularization in the new media era.

Jinyun Mountain, as one of the landmarks of Beibei.

You should be familiar with it or have been there many times.

But being there many times doesn’t mean you know it.

It is not enough to go to the magical place of Jinyun Mountain once.

Today, Wenlvjun takes you to unlock the new gameplay of Jinyun Mountain.

Feel the Jinyun Mountain that I have never seen in my circle of friends.

Put away this strategy.

On the arrangement of one-day tour in Jinyun Mountain

Tuyuan | Leisure Beibei

This Jinyun Mountain, which is the closest to human fireworks.

No sea of people, no hustle and bustle.

Even the daily chicken feathers

It seems too far away

Visit Jinyun Mountain again this time.

To discover her new beauty

Tuyuan | Leisure Beibei

Twilight drums and morning bells, mountains and waters.

The reflection of the lake embankment makes each other interesting.

There is always a place here.

Satisfy your beautiful imagination　

Tuyuan | Leisure Beibei

Jinyun Mountain in Chongqing in Early Summer

Mountain after mountain, green is about to drip

When the morning mist awakens the sleeping mountain forest

Strolling on the Qingshiban Road in Jinyun Mountain

Time for a cup of coffee.

Come and feel this noisy and prosperous mountain forest

How to wake up from the quiet

Jingangbei historical block

Good natural ecology is the background color.

Starting from Beibei City, it takes about 15 minutes by car, and then you come to the Jingangbei located on the bank of Xiajialin River in Jinyun Mountain. Here is the quiet and leisure of an ancient village, where the traces of time are condensed and concentrated; It is comfortable to walk along the village to the river and take a turn at the river dam.

Tuyuan | Leisure Beibei

There is a quaint stone bridge in the historical block of Jingangbei, and the stream under the bridge is still gurgling. The leafy trees of Huangge can be seen everywhere, and the green leaves form a natural "awning". The streets have become cleaner, and the old buildings along the road have been carefully repaired, which is more rich in historical charm. The old trees in the block that are more than 100 years old have been properly protected. These precious ecological elements will also become the most distinctive highlight of the historical block of Jingangbei.

Tuyuan | Leisure Beibei

King Kong Monument flourished in the Qing Dynasty, located at the foot of Jinyun Mountain and beside Jialing River. It was first developed by transporting coal. Renovation began in April 2018, and the core area covering an area of 50 mu is expected to open to the public as soon as October this year, and the entire historical block will also be opened during the year.

Yumingjian

Shan Ye fun recreation punch card place

All the way up from the foot of the mountain, everything is green, and the retreating jungle is silently watching every traveler with the starlight lake …

Tuyuan | Leisure Beibei

Go to Yuming River, where native plants such as Patchwood, Pennisetum and Huang Jinju dance with the wind and are full of wild interest.

Yumingjian takes "evening rain Rising Autumn Pool" as the theme, and combines the misty night rain and mountain valleys to form a fun and leisure punching place in Shan Ye with "rainy feelings".

Daihu & Beibei District New Age Civilization Practice Ecological Civilization Branch

You don’t know the niche punching place.

The water is clear and green as Dai, so it is called Dai Lake. Here you can clearly see the fish wandering in the lake, walking around Daihu, and the whole person is comfortable physically and mentally; Looking around, the lake is shaded by trees, the lake is rippling with blue waves, the green algae at the bottom of the lake are uneven, and the lake embankment reflects each other.

Tuyuan | Leisure Beibei

There is also a treasure punching place near Daihu-Beibei District New Era Civilization Practice Ecological Civilization Sub-center.

Tuyuan | Leisure Beibei

Looking at the location of the ecological civilization sub-center, you think this is a homestay or a cafe, or maybe a book. In fact, it is not only an eco-art exhibition of "turning waste into art" but also a museum about the evolution of Jinyun Mountain, which began to open to the public free of charge this year.　

Open hours

Tuesday to Thursday: 10: 00-16: 00

Saturday to Sunday: 10: 00-16: 00

Monday and Friday: closed

Tenglongya viewing platform

Scenic landmarks in Jinyun Mountain　

"Nanshan One Tree Observation Deck" is the punching place of "online celebrity" overlooking the landscape of Chongqing and enjoying the night scene. Now, a scenic landmark-Tenglongya has been added to Jinyun Mountain in Beibei, which consists of Lanjiangtai, Linshangge and Tenglongya Garden.　

Tuyuan | Leisure Beibei

Linshangge has 9 floors and is 24.3 meters high, which shows the architectural style of Bayu. Climbing on the forest pavilion, you can enjoy different scenery on each floor. Standing at the highest place in the attic, you can have a panoramic view of Beibei city, and you can have a panoramic view of the beautiful scenery of the "Eight Bridges and Green Buildings".

Tuyuan | Leisure Beibei

In the Tenglongya Garden, there is also a waterfall landscape created by the height of the terrain, with flowing water and shade, which has a unique scenery.

Mazhongzui watching the clouds from the wind viewing platform

Xinjin online celebrity glass corridor bridge　

The red dot of Xinjin. com looks at the cloud observation deck with the wind, and it is backed by mountains, with a wide view on three sides. Standing on the glass corridor, the green hills at the foot are like dye, and the bamboo sea is undulating. Looking around, the scenery in Beibei City is panoramic. You can also experience the excitement of hanging feet here!

Tuyuan | Leisure Beibei

Tuyuan | Leisure Beibei

Jinyun Mountain Scenic Area

Finally, when you arrive at the scenic spot, you can choose your own preferences to climb the mountain. From north to south, there are 9 peaks in Jinyun Mountain, such as Asahi Peak, censer Peak, Lion Peak, Juyunfeng Peak, Ape Peak, Lotus Peak, Pagoda Peak, Jade Peak and Xizhao Peak. Of course, the Jinyun Temple hidden in the mountains is also a must-see attraction. More beauty of Jinyun Mountain is waiting for you to discover it yourself ~

Tuyuan | Leisure Beibei

Collect it quickly.

Share with friends

Punch in and take photos ~

Original title: Refresh the new gameplay in Jinyun Mountain! Take away the most complete play raiders!　 　 　 　 　 　 　 　　

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Recently, another virus began to wreak havoc, that is, respiratory syncytial virus. Recently, many children with bronchitis, asthmatic bronchitis, bronchiolitis and bronchopneumonia were treated in the pediatric clinic and ward of the Public Health Center, and the culprit-respiratory syncytial virus was found!

What is respiratory syncytial virus?

Respiratory syncytial virus (RSV) is the most important virus pathogen that causes acute lower respiratory tract infections (ALRTI) in children under 5 years old worldwide. Almost all children have had at least one RSV infection before the age of 2.

RSV is an RNA virus, and the dominant virus strains mutate every year, which is easy to be repeatedly infected. It is highly contagious, mainly transmitted through coughing and droplets and close contact (such as touching and kissing infected people), and can survive in vitro for several hours on contaminated desktops and toys. And not only people of all ages are susceptible to it, but it can’t be prevented by vaccines, which makes people hard to prevent.

RSV is a seasonal epidemic virus. In the north of China, it is mainly prevalent from November to April of the following year (mostly in January and February). In the warm and humid south, the incidence rate is relatively high all year round, but it is relatively higher in summer and autumn.

RSV infection is the primary cause of hospitalization of infants with viral respiratory tract infection, which seriously endangers children’s health, especially for premature infants and infants with congenital heart disease or primary immunodeficiency.

RSV infection is the most easily involved in respiratory system, and its main mechanism is airway obstruction, bronchial smooth muscle spasm and subsequent airway hyperresponsiveness, and its clinical manifestations are mostly cough, wheezing and fever.

RSV is mainly transmitted through nasopharyngeal mucosa or ocular mucosa contacting with virus-containing secretions or pollutants. Direct contact is the most common route of transmission, but droplets and aerosols can also cause transmission, so hand washing and contact protection are important measures to prevent transmission.

What are the symptoms of RSV infection?

The incubation period of RSV infection is generally 2~8 days, and symptoms usually appear after 4~6 days of infection.

After most healthy children are infected with RSV, the mild symptoms and early symptoms of infection are similar to the common cold, with symptoms such as nasal congestion, cough, sneezing, runny nose and low fever.

With the development of the disease, severe cases will have dyspnea or shortness of breath, wheezing, irritability, loss of appetite, and even respiratory failure and heart failure.

Especially for premature infants or children with severe heart disease, lung disease and abnormal immune function, it is very dangerous to be infected with RSV. In addition, RSV is the main pathogen of pneumonia and bronchiolitis in infants before 2 years old (2~6 months old is the peak age of bronchiolitis), so parents should never take it lightly.

RSV is self-limited. For children with normal immune function, family care can be done when mild infection occurs, such as feeding the baby a small amount of water many times, using a humidifier properly, dropping a little physiological saline into the baby’s nasal cavity, and sucking with a nasal aspirator after a few minutes to help the baby discharge secretions from the nasal cavity.

Note: If the symptoms are serious, you must go to the hospital in time if the following symptoms appear:

1. Body temperature > 38.5℃, and it does not go back repeatedly;

2. The baby is fidgety, crying and has a poor mental state;

3. The baby’s appetite is greatly reduced or refuses to eat, and dehydration is observed;

4. The suction frequency is greater than 60 times per minute;

5. Dyspnea, shortness of breath, (observed that the baby’s nostrils are open and breathing hard, and the muscles under the ribs or chest are depressed inward, etc.) (as shown below);

How to treat RSV infection?

There is no specific medicine at present. Clinically, symptomatic support treatment is usually adopted, with isolation nursing and symptom relief as the main methods.

○ What should I do if my baby has a fever?

If the baby’s temperature is above 38.5℃, the high fever persists and there are uncomfortable symptoms, you can take ibuprofen or acetaminophen orally.

○ What about coughing and runny nose?

If the baby has cough and runny nose, parents are not advised to use cold medicine, cough medicine or antibiotics at home without authorization. Instead, it is recommended to consult a doctor and take the medicine according to the doctor’s advice to prevent other adverse reactions.

Because RSV often invades the lower respiratory tract, unlike the general upper respiratory tract infection, parents must consult a doctor before taking the medicine!

○ Can I use antiviral drugs?

If it is a baby with severe RSV infection, antiviral drugs may be used, but they also need to be used according to the doctor’s advice.

○ Will there be sequelae?

Mild prognosis is good: babies with mild symptoms don’t have to worry after infection, and the prognosis is usually good.

Attention should be paid within 12 months: RSV is highly related to bronchial asthma, the most common chronic respiratory disease in children, especially when infants under 12 months are infected with RSV.

Studies have confirmed that children infected with RSV in infancy are four times more likely to have asthma or repeated wheezing in the future than those who are not infected, and severe lung function damage can last for more than 10 years. If most children are infected with RSV within one year of birth, they will be infected repeatedly for the next three years.

How to prevent RSV?

● Keep children’s hand hygiene: don’t rub your eyes and nose after going home, and wash your hands in time.

● Wear a mask in public places: remember to wear a mask in schools, hospitals, cinemas and crowded places without ventilation. If it is a baby who can’t adapt to masks, parents should keep a distance from others.

● Keep indoor air circulation: convection ventilation can be used when the air quality is good and the weather is warm; Ventilation for several times in cold weather, and the time is kept at about a few minutes; It is not recommended to open the window for ventilation when the air quality is poor.

● Reducing irritating gases such as second-hand smoke and formaldehyde in the environment can protect the immune function of the baby’s airway mucosa.

Official micro of public health center

Your family’s health consultant

Long press

Identify two-dimensional code

Original title: "Public Health Science | Parents need to pay attention-respiratory syncytial virus infection is coming again! 》

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Some time ago, a rock music festival was held in Xinxiang, Henan Province. Perhaps many people are interested in this contrast. In fact, Xinxiang is a well-known "hometown of rock and roll". After all, its English name can also be "New York". In 1998 and 1999, Xinxiang held China New Music Concert twice; Zhengzhou Railway Bureau also set up a rock train. It is said that the opening of Xinxiang Hotel invited all rock bands. So, how did Xinxiang, an ancient land located in the Central Plains, plant the rock gene?

Xinxiang street at night. Photography /CZAN Chen, source/figure worm creativity

Mu Ye and Xinxiang

Xinxiang, known as Mu Ye in ancient times, has a long and profound history, with Taihang in the north and Yellow River in the south. Zou Heng, a famous archaeologist in China, once said: "There are three breakthroughs in the study of Xia culture in Henan, the first is Erlitou in Yanshi, the second is Zhengzhou, and the third is Xinxiang." During the Shang Dynasty, Xinxiang belonged to the land within the capital and was the base of the origin and rule of Shang tribes. The Battle of Makino, which led to the demise of the Shang Dynasty more than 3,000 years ago, also took place in Xinxiang.

Schematic diagram of Makino Battle

In the Western Zhou Dynasty, there was a city in the middle of Mu Ye, which was sealed by Guan Shu, the brother of Zhou Wuwang, and an important vassal state in the eastern part. During the Eastern Zhou Dynasty, most of Xinxiang belonged to Wei, while the west belonged to Zheng and Jin. In the late Spring and Autumn Period, the State of Jin was powerful. In 632 BC, the army of the State of Jin fought with Qin, Qi, Song and Chu in Chengpu (now southwest of Juancheng County, Shandong Province), and the Chu army was defeated. After the Battle of Chengpu, the State of Jin joined forces with the kings of Qi, Lu, Song and Wei in Jiantu (now in Yuanyang County, Henan Province), which was called "the alliance of Jiantu" in history. Wang Jizheng of Zhou Xiang also sent representatives to participate in the alliance, and Jin Wengong was named as the overlord. In order to further consolidate the hegemony of the Central Plains, the State of Jin was again a vassal in Wen (now in wen county, Henan Province), and King Xiang of Zhou was also invited to the meeting. During the Warring States period, Xinxiang belonged to Korea first, and then to Wei. Xinxiang recorded the stormy times of diplomatic mediation.

Wei and Zheng in the Eastern Zhou Dynasty. Source/Tan Qixiang Edition Atlas of Chinese History

After the Qin Dynasty, Xinxiang’s administrative planning gradually became clear. In the Qin Dynasty, Xinxiang belonged to Sanchuan County, and in the Western Han Dynasty, the whole country set up the Sili Department and the Thirteen Secretariat Departments. The major part of Xinxiang belonged to Hanoi County of the Sili Department, while the eastern part belonged to Chenliu County of Henan County and Yanzhou Secretariat Department, and set up Ji County, Gongxian County, Huojia County, Yuanwu County, Yangwu County, Juanxian County, fengqiu county County and Zizyphus County. In the second year of Taishi in the Western Jin Dynasty (266), Ji County was set up, and Ji County (southwest of Weihui City, Henan Province) was ruled. Its jurisdiction is roughly equivalent to today’s cities and counties such as Weihui City, huixian city, Huojia County, Xinxiang City and Xiuwu County.

In the fifth year of Taihe in the Eastern Jin Dynasty (370), Murong Zang, the younger brother of Murong Wei, the former emperor of Yan State, met the former Qin army and built a new city called Xinle City. In the sixth year of Emperor Kai of Sui Dynasty (586), Xinxiang County, now the old town of Xinxiang City, was established, belonging to Hanoi County. Although the organizational system has changed since then, the basic pattern of Xinxiang has not changed. In the late Qing Dynasty, compared with coastal towns, Xinxiang was less impacted by western culture and its social form did not change significantly. At the beginning of the 20th century, with the intersection of Beijing-Han Railway and Daoqing Railway in Xinxiang, the urban development of Xinxiang entered a new historical period.

The map of Xinxiang county in Henan province during the Republic of China shows that Xinxiang county is located at the intersection of two railway lines at this time. Source/(Republic of China) "Continued Records of Xinxiang County", Volume 1, "Illustration", "China Local Records Series, North China Place" No.473, printed by Chengwen Publishing House Co., Ltd. in 1976 according to the 12-year edition of the Republic of China.

Rock and roll and Xinxiang

Xinxiang not only records the political, economic and historical development of China, but also is the carrier of opera and music. As a major province of opera, Henan Opera and local operas are equally popular in Xinxiang. Coupled with the gradual convenience of transportation in the late Qing Dynasty and the interweaving of various cultures, Zhongzhou Drum, Kaiming Drum, Xihe Huai Bang Opera, Xiangfudiao and other operas have always prevailed. Xinxiang people have a strong "artistic cell", and many middle-aged people will learn to play drums and guitar after they get married.

After the reform and opening up, both the city and social culture have quietly changed, and Xinxiang was also enlightened by the surging Chinese rock and roll at that time. If you meet someone who wears leather clothes and has long hair on the street, you will often ask the other person: "Do you listen to rock?"

In 1986, with the spread of "Northwest Wind" series of songs such as "Xintianyou", "Loess Plateau" and "My Hometown in Love", the "Northwest Wind" series of works formed the first wave of local music culture. The rise of rock and roll also took place in 1986, and some scholars even pointed out that "Nothing" and "Journey to Heaven" should be the source of "Northwest Wind".

Since its birth, rock and roll is a special cultural symbol, which always appears in a posture beyond the ordinary world and soars towards the height of spirit. Rock songs have a wide range of expressions, including deep historical nostalgia like Dream Back to the Tang Dynasty, Zhang Chu’s personal concern for fate, and Black Panther band’s realistic reflection and confusion. Generally speaking, they all have a spirit of inquiring and reflecting on reality and life. As a "new force" in pop music, rock and roll has opened up new space for the poetic latitude of lyrics and the functional latitude of songs.

Screenshot of the song MV of the Tang Dynasty band "Dream Back to the Tang Dynasty"

Under this background, Xinxiang is also interacting with the rock era. On the evening of April 11th, 1998, Xinxiang Sports Center was brightly lit, and the first "China New Music Concert" was held here. It is said that the concert was originally planned to be held in a disco in Zhengzhou, and three rock bands were invited to make a platter. But Liaoyuan Huang, who has held several performances in Beijing, said: If you want to play, play big! So nine bands were booked. When the organizer heard nine bands, he was blindsided, knowing that a disco could not be put down, and considering that Zhengzhou’s approval must be very troublesome, he suggested moving to Xinxiang Sports Center, which can hold 30,000 people, to bring economic benefits to small places and enhance cultural awareness. That’s it.

God of Light is Black Panther band’s second music album, which was released in August 1993.

Someone once recalled: "In 1998, Chinese rock went to Xinxiang, Henan Province to perform, which was a great gathering of Chinese rock since 1993, which was particularly exciting. Because rock musicians perform in bars in bits and pieces, there is no such stage for them to show. " "In order to make the rock performance more smooth, so let Sun Nan start and sing" Red Flag Fluttering ". (There are also) Tang Dynasty, reincarnation, sobriety, zero point, overload, cobra, Bao Jiajie, compass and 1989 band, etc. "

This is a rock festival at the end of the 20th century. All musicians are full of joy. The exciting rhythm is knocking on everyone’s heart. The exciting power makes people excited. According to Liaoyuan Huang, the planner of this event, "When I planned Xinxiang rock concert in 1998, there was no rock music festival in China, and the outdoor performances of nine bands were the best at that time." On that night, Wang Feng changed "Good Night, Beijing" to "Good Night, Xinxiang", Gao Qi and Overload sang "Let Every Night Be Filled with the Flame of Love", and the audience lit lighters … The whole performance lasted for nearly four hours, and the atmosphere at the scene was climaxed. Taking this opportunity, at the request of fans, the Passenger Transport Department of Zhengzhou Railway Bureau specially designed the "Qiyuan" fan train: the train number is 680 and 681, and the fare is 11 yuan.

In 1998, China New Music Concert was held in Xinxiang, Henan Province. Source/Rocker

Because the first session was so successful, the next year, the second "China New Music (Xinxiang) Concert" arrived as scheduled. Different from 1998, Cui Jian and Black Panther band also joined the performance. In addition, Huaer Band and the rap group "D.D. Rhythm" founded by Dai Bing and Tianbao also joined in. Because of this performance, the musical horizons of fans in Xinxiang and even in China have been broadened again.

In the year of the real end of the century, when Cui Jian sang "Nothing", the whole stadium was in chorus. That kind of feeling, everyone present will remember it vividly in retrospect. For those who love rock and roll, this musical expression conveys the most direct emotional catharsis.

Cui Jian’s "Nothing" scene, 1992

The rock show for two consecutive years has made Xinxiang the base of Chinese rock. However, today we are familiar with the rock bands coming from the 20th century, and almost all of them enjoy the excitement brought by music with the audience in Xinxiang Sports Center. The two performances not only established Xinxiang’s position in the hearts of national rock fans, but also injected the immortal rock spirit into the city.

Why did a "China New Music Concert" become a special performance of rock music? It turned out that at that time, in order to avoid the rebellious meaning of the word "rock", most rock performances in Xinxiang were named "new music", and the two were corresponding. Liaoyuan Huang mentioned in "Ten Years of Rock on the Road": "One night in 1997, I finished the planning of’ 98 China New Music Concert (Xinxiang)’, because rock music was still a sensitive word at that time, so we chose the nondescript word’ new music’ as a cover." Some articles pointed out that those years coincided with the vigorous development of Xinxiang’s private economy, and all kinds of supermarkets and restaurants invited bands to perform when they opened their doors. Even when Huimian Noodles Pavilion opened, the bands at the door played rock and roll. Compared with Zhengzhou, Xinxiang has less pressure in life and musicians have enough time to make their own music. In big cities, however, you can’t make money as a band, and musicians are often busy running a venue or making a cover Shang Yan to support their families. Yang Baobin, a veteran rocker in Xinxiang, said that in Xinxiang, there are few people who use music to bluff, or feel that making music is superior. Generations of bands and organizers have been silently relaying in Xinxiang for nearly 20 years. Although the mentality is different, we play together and act together. Perhaps this is also the main reason why the organizer had to transfer Zhengzhou disco to Xinxiang Stadium when Liaoyuan Huang wanted to "play a big game".

Afterlife and Xinxiang

After that, Xinxiang not only attracted a large number of rock singers to hold concerts, but also gave birth to many new forces of rock music. For example, Crazy Doctor Band, which was founded in Xinxiang in 2008, can be generally classified as "post-punk". In 2019, they released the single "Will you still hate me when I die one day?" The whole song was dark and cold, and the lyrics full of rebellion expressed the singer’s thinking about society. Some fans commented: "Support our band in new york, the Netherlands." "Holland" is the homonym of Henan, and "new york" is the nickname of Xinxiang for fans.

The seemingly playful expression shows people’s attachment to the rock atmosphere of this city. In addition, there is Pumpkins Little Pumpkin Band, which was founded in 2009. In their music, you can see many old punk figures in Europe and America in 1970s (such as The Stooges, Johnny Thunders, etc.). In 2005, led by the local record company "Revolver Records" in Henan Province, together with Xinxiang Survivor, Attempted, Medusa and several other Henan bands, released a collection "Race to the Central Plains". Twelve years later, South of the River, a new music collection of the Central Plains, continued the musical vitality of Xinxiang and the Central Plains. In this collection, which is led by the musician Renzi Fu, Remy Band, Godfather Band, Xiatu Band, Little Pumpkin Band, singers MIMO, Tian Qigao, Xiaonan, Wang Huafeng, Ye Lin and other groups of Central Plains music representatives joined in, and a total of 10 outstanding original works were included. The young rock power has brought a different kind of youth and rebellious color to Xinxiang.

The cover of South of the River

Rock music is rooted in Xinxiang and closely connected with it. In 2021, Henan suffered from torrential rains and floods. During this time, the whole country rushed to support the disaster area, and there was such a group of people in the rock circle. They not only donated money, but also came to Xinxiang to actively participate in the rescue work. Song Jie, a guitarist, and bands such as Da Wenxi, Crazy Doctor, Pumpkin, Mazi Ma, Sevenjoys, Cyclops, Nano Sound Shell and Red Scarf all participated in the on-site rescue in Xinxiang. This city, located in the north of Henan, is witnessing the growth and prosperity of rock and roll young people.

From Yangshao culture and Longshan culture to the battle of Makino and Guandu, from the first "China New Music Concert" to "Chasing the Deer in the Central Plains" and "The South of the River", Xinxiang recorded the long history of ancient China, and also painted a colorful stroke in the history of Chinese rock. It is conceivable that in the near future, China’s rock and new music will be sung in Xinxiang and the Central Plains for a long time.

References:

General situation of Xinxiang, Xinxiang Municipal People’s Government.

Yue Shi. Protection and Path of Historical and Cultural Resources from the Perspective of Regional Culture —— Taking Xinxiang City of Henan Province as an Example [J]. Journal of Henan Institute of Animal Husbandry Economics, 2020,33(02):53-58.

Cui Jian and Wang Feng testified that Xinxiang is the "Rock City".

Rescue the hometown of rock and roll in the flood, Xinxiang, Henan.

Ten groups of musicians from Henan gathered in Zhengzhou, and the compilation "South of the River" premiered.

Ye Dawei. From "Rock" to "Buddhism": An Interpretation of the Evolution of Youth Subculture in Pop Songs [J]. Contemporary Youth Studies, 2020,No.365(02):23-27.

Lu Zhenglan. Song Creation and Development in the Past 40 Years of Reform and Opening [J]. Journal of Sichuan Normal University (Social Science Edition), 2018,45(05):38-46.

Many people don’t know that Xinxiang is still the hometown of rock and roll.

Shan Qi. Walking on the edge of entertainment [M]. Writers Publishing House .2006.87.

The Outbreak of Rock and Roll —— Xinxiang, Henan Province

END

Author | Ma Zichen

Editor | Zhan Qianhui

Proofreading | Torch Li Dong Zhang Bin Gu Yue Miao Yiqi

* This article is the exclusive manuscript of "National Humanities History", and readers are welcome to forward it to the circle of friends.

National Humanities History magazine

Original title: "China Rock Base, Why Xinxiang, Henan? 》

Read the original text

The Prime Minister Liu Luoguo, which was broadcast in 1996, was popular all over the country and influenced a generation of viewers.

Liu Luoguo did exist in history. He was a famous minister of the Qing Dynasty, Liu Yong. After Qianlong and Jiaqing dynasties, he was an official with He Shen.

What is being broadcast nowLiu Yong Chasing the CaseIt is also his story, and the styles of the two plays are somewhat similar.

　 　 　 　

　 　 　 　

In today’s market environment, you can also see the high-cost drama starring He Bing, and you can also see the long-lost Qing Dynasty official drama. The excitement and expectations have been raised a lot, but7 episodes, it is hard to hide disappointment.

The official dramas and historical dramas of the Qing Dynasty were once one of the most vigorous dramas in the history of China’s TV dramas, which contributed countless classics, showed humanistic concern, and even included people’s wisdom and enlightenment. But now it is almost extinct, and it is hard to appear, and it has lost its former glory and strength.

Welcome to the "Phoenix Net Index-Comprehensive List of Movies" applet, and express your views on "Liu Yong Chasing the Case" ~

Long-lost historical drama

At the end of the last century and the beginning of the new century, China is at the juncture of economic transformation, and all kinds of ideas collide, and the creation of various types of domestic dramas has reached its peak. Among the flowers, historical dramas are also included.

In 1991, Taiwan Province and the mainland co-produced "The Story of the Dragon", which opened a precedent for the drama of the mainland and became popular on both sides of the strait.

　 　 　 　

　 　 　 　

Since then, there has been an upsurge in the creation of historical dramas, and a series of classic dramas have been born one after another.

In addition to Prime Minister Liu Luoguo in 1995, there are Kangxi’s Private Visit in 2000, Ji Xiaolan with Iron Teeth and Copper Teeth in 2001, Li Wei’s Being an Official, and Happy Doctor in 2003.

These historical dramas are in sharp contrast with some historical dramas at that time, such as Yongzheng Dynasty (1999), Yu Chenglong, a generation of honest officials (2000), Kangxi Dynasty (2002), The Granary of the World (2002) and Towards the Republic (2003).

The so-called "joke" refers to the fact that the creator does not completely rely on the authenticity of historical records, and does not abide by the limitations of historical environment on characters; It focuses on the attitude of the creators, includingThe unconstrained folk imagination and free play.

Just like the ending song "Things in the Story" of "Prime Minister Liu Luoguo" sings-

Things in the story, if you say no, you don’t, yes and no. What happened in the story may be true. What happened in the story may have never happened. In fact, a story is a story, and a story is a story.

　 　 　 　

　 　 　 　

Of course, joking doesn’t mean nonsense. Just as Liu Heping, a famous writer of historical dramas, said, "The audience likes joking, but we also have a principle: the characters emphasize joking, but the historical background is real and the audience will."Feel the true sense of history under the fictional comedy plot.That is to say, to play well, but also to chew. "

The beauty of a joke drama mainly stems from its comic effect and the rivalry between officialdom, which often forms a contrast through the harmonious conflict between characters.

　 　 　 　

　 　 　 　

The "chewing head" of the joke drama lies in that it relies on the real historical background and characters, and through the confrontation, balance and compromise between the monarch and the minister and between loyalty and traitors,Deeply understand the essence of China’s ancient officialdom.

For example, in the relationship between Ji Xiaolan-He Shen and Liu Yong-He Shen, Gan Long is the mediator.

In many storms, He Shen always got away with it. It’s not that Qianlong didn’t know he was corrupt, but that Qianlong enjoyed He Shen’s flattery and was handy, and he also needed to use He Shen to balance the courtiers’ relationship. The subtlety between the monarch and the minister is quite interesting.

In "Ji Xiaolan with Iron Teeth and Copper Teeth", the part where the sand is scattered by the dragon is praised so far.

　 　 　　

Comedy and satire are just one side of this kind of drama.

The whole drama "Prime Minister Liu Luoguo" laughs and curses, criticizes the current disadvantages, and finally ends in sadness and desolation. The prosperous time has been obviously decadent, a generation of emperors have white hair and tears, and a generation of famous ministers have gone home.At that time, the drama could tell the rise and fall with jokes.

　 　 　　

　 　 　 　 　

Liu Yong Chasing the Case is better than nothing.

Liu Yong Chasing the Case has many shortcomings, but the opening story is very interesting.

During the Qianlong period, there was a pile in Shandong."False transmission of imperial edicts and seizure of officials"In the major case, Cai Yongchang, the magistrate of Dongchang, was seized by a bunch of "fake officials" and mysteriously disappeared on his way to Beijing to plead guilty. Millions of stolen silver also disappeared.

Hearing this, Qianlong (Huang Haibing) was furious and ordered Liu Yong (He Bing) to solve the case or deal with it according to law, and arranged for Fu Guotai (Li Naiwen), the governor of Shandong Province, to cooperate with He Shen (Alvin) in the investigation.

　 　 　 　

This big case is interspersed with countless small cases.It is a challenge for the screenwriter’s ability to control.

The category of "Prime Minister Liu Luoguo" and "Li Wei is an official" is closer to the unit drama, and every few episodes tell a short story.

Liu Yong Chasing the Case still retains several core features of Liu Luoguo, the Prime Minister: comedy, detective work, and the appearance of officialdom.

But in either case, it’s a little tasteless.

In the past, there were central protagonists and villains in official operas, so Ji Xiaolan’s story can be without Liu Yong, but there must be He Shen and Liu Yong’s story. One is right and one is evil, and the contradiction runs through.

But in Liu Yong Chasing the Case,Who are the core villains and what power they have? So far, they have not been shown.He Shen and Fuguotai are all like a cursory tour.

　 　 　 　

　 　

Liu Yong Chasing the Case claims to be a light comedy, and Liu Luoguo in Prime Minister Liu Luoguo also has humor, but he is a kind of cold humor. Most of the time, Liu Yong is a wise image of the elderly, and the comedy part is mainly played by He Shen.

　 　 　 　

　 　

In "Liu Yong Chasing the Case", He Shen doesn’t appear much at present, and the comedy mainly focuses on Liu Yong and his servant Xi ‘er. The two of them will talk about simple and honest Shandong dialect for a while, and Beijing dialect that will tease the poor for a while, which is a bright spot.

So compared with Liu Yong in Li Baotian,He Bing version of Liu Yong has a little more humor, which will make people feel a little "hard" in the performance.

For example, Liu Yong fascinated Fu Guotai and He Shen so as not to interfere with the trial of prisoners. After Fu Guotai and He Shen woke up, Liu Yong also pretended to be drunk.

Here, He Bing’s version of Liu Yong’s performance is a little "playing the fool and being fully distracted", and he always smiles at the two adults.

　 　 　　

On the contrary, He Shen and Fu Guotai appear "stable".

　 　 　

It’s not that He Bing’s performance is not good. Frankly speaking, few actors can hold the role now. But rather,The writer’s positioning of Liu Yong forced the actors to express their comic features.

Exploring the case is the weakest part of Liu Yong Chasing the Case.

Especially in contrast to He Bing’s Da Song Tiaoguan, the handling of detective cases in Liu Yong Chasing Cases is relatively childish.

All kinds of cases in the play-mainly the bizarre deaths of people related to the cases-have only one purpose, which hinders Liu Yong from seeking the truth and drives Liu Yong away from Shandong. But in the first few episodes, the main cause of bizarre death turned out to be being bitten by a poisonous insect.

　 　 　　

At this time, the role of poisonous insects is almost "fantasy": poisonous insects can not only bite people accurately, but also basically die as soon as they bite people. The method of detoxification is more mysterious, and drinking some water will be fine.

　 　 　 　

　　

This is actually the writer’s laziness or incompetence.It is impossible to conceive suspense more skillfully and reasonably., can only come up with a fantastic poisonous insect.

Looking at the leopard from a peep, the design in the play looks like that, but it can’t stand scrutiny.

For example, in the first episode, Liu Yong and Xi ‘er were fishing by the river, and they saw several bandits carrying a girl. They were unarmed and didn’t know kung fu. As a result, Liu Yong shouted the illusion on the spot, causing the bandits to want to kill them. If a bodyguard hadn’t suddenly appeared, the first episode would have been the finale.

　 　 　

Officialdom in the sky, "Liu Yong Zhuan" also has details.

For example, at the beginning, Ganlong recruited Liu Yong to investigate the case, and asked Liu Yong in front of Fu Guotai: Fu Guotai didn’t find out for a month, should he be punished?

　 　 　 　

Liu Yong was careless and didn’t jump into the pit dug by Qianlong, nor did he embarrass Fu Guotai face to face.

　 　 　 　

this isPhilosophy of getting along with officialdom, an emperor will not really cure the crime of wealth and prosperity; Second, Fu Guotai is the governor of Shandong, and he is deeply rooted in the local area. Liu Yong cannot offend him if he wants to go to Shandong. Third, Liu Yong may not be able to do a good job in the case. Now he helps the rich and the country get away with it, and he will have a way out in the future.

However, in the past, there were more profound criticisms on the relationship between monarch and minister and the people’s hearts. For example, many screenshots in Ji Xiaolan with Iron Teeth and Copper Teeth were widely circulated.

　 　 　

In contrast, Liu Yong Chasing the Case is still less penetrating and profound at present. itIn essence, it is a story of loyal monarch and loyal minister..

　 　 　　

playBai Bing plays Gege and Liu Yong’s wife.At present, it seems like afaulty stroke (in calligraphy). This lady is unruly and willful. Liu Yong went to Shandong to handle a case on orders, but she didn’t dare to tell her, for fear of being stopped.

My wife thinks that Liu Yong is in danger in Shandong, so she wants to bring him back to Beijing, which has little effect except making the audience angry and keeping the water running for a long time.

　 　 　　

But in any case, "Liu Yong Chasing the Case" made many viewers feel.Retro atmosphere.

In recent years, under the impact of other types of TV dramas, the influence of the "ancient restrictions" and the tightening of the creative environment, this kind of joke drama relying on the real historical background and characters has almost disappeared. If there is, it may also face difficulties in broadcasting.

Poor creation cultivates poor aesthetics, and also makes works with substance lose the market.

What’s more, in the era when Xiaorou plays the leading role and powerful actors play the supporting role, there are also dramas in which Mesozoic actors take the lead and have no traffic, and it is true that one is missing.

Liu Yong Chasing the Case can only be said that talking is better than nothing.

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Original publicity center, Zhejiang University Children’s Hospital of Pediatrics Department

"The child was hospitalized for pneumonia several times this year.

I really don’t want to experience it again … "

"I get nervous when I see him coughing."

In winter, the temperature changes greatly, and respiratory diseases gradually enter a period of high incidence. Unfortunately, bacteria, viruses and mycoplasma can’t be prevented. Many parents have already started to feel anxious ahead of time, and they have said that their children have been accidentally recruited several times this year, which is really scary.

After many inquiries, I heard that the vaccine is effective in preventing pneumonia, but many parents still have doubts about it.

"In response to pneumonia in children, vaccines are indeed the key." Ji Chai, deputy director of the Children’s Health Department of Zhejiang University Children’s Hospital, said, "All kinds of infectious sources such as viruses, bacteria, fungi and mycoplasma can cause pneumonia. The more common pathogens are influenza virus, respiratory syncytial virus, adenovirus, streptococcus pneumoniae, Haemophilus influenzae type B (Hib), mycoplasma pneumoniae and so on. At present, there are corresponding vaccines for influenza virus, Streptococcus pneumoniae and Haemophilus influenzae type B (Hib), which can help children establish an immune barrier against these three pathogens and effectively reduce the probability of severe illness. "

So, which children need to be vaccinated? Is it necessary to vaccinate them all? How to choose a variety of influenza vaccines, pneumonia vaccine and Hib vaccines? When is the best time for vaccination? We specially invited Deputy Chief Physician Ji Chai to answer the questions of parents in detail.

Ji Chai, Deputy Director of Child Health Department, Deputy Chief Physician.

Specialty: Follow-up of high-risk infants, immunization consultation and follow-up of children with William syndrome.

Research fields: nutrition and development monitoring of premature infants, phenotype and gene related research of William syndrome, and safety and effectiveness of vaccination for children with special health conditions.

Outpatient time: Wednesday and Friday morning, Thursday afternoon (lakeside campus)

01

What is the principle of vaccine?

Vaccine is a preventive biological product made of pathogenic microorganisms (such as bacteria, viruses, etc.) and their metabolites by artificial attenuation, inactivation or transgenic methods to prevent infectious diseases. The vaccine retains the characteristic that pathogenic microorganisms stimulate human immune system, that is, immunogenicity. When people are vaccinated, the immune system will produce certain protective substances, such as immunocompetent substances and corresponding antibodies. When the human body comes into contact with the corresponding pathogenic microorganisms again, the protective substances produced will play a role in preventing the harm of pathogenic microorganisms to the human body.

02

Which children suggested playing?

Influenza vaccine/pneumonia vaccine /Hib vaccine?

Influenza vaccine: Influenza is different from common cold. It is an acute respiratory infectious disease caused by influenza virus, which is very harmful to human health. People are generally susceptible to influenza virus, and timely influenza vaccination is an effective means of prevention.

If children over 6 months old have no contraindications to vaccines, it is recommended to get the flu vaccine.

Pneumonia vaccine: Pneumococcal infectious disease is one of the common diseases. According to the survey, the incidence of pneumonia caused by Streptococcus pneumoniae in children and the elderly over 60 years old is three times that of young people, and about 2.5 million people suffer from pneumococcal pneumonia every year.

Pneumococcus is widely distributed in nature, and it is a typical opportunistic pathogen, mainly transmitted directly by respiratory droplets or infected by colonization bacteria. 30% or more healthy people will carry pneumococcus in the nasopharynx without getting sick, but when the body’s resistance drops, pneumococcus is easy to take advantage of it and cause serious diseases such as pneumococcal pneumonia, otitis media, meningitis and septicemia.

Children under 5 years old, especially infants under 2 years old, are particularly vulnerable to this pathogen because their autoimmune function is not yet fully developed. Secondly, the elderly over 65 years old and people with low immunity are also high-risk and susceptible groups of pneumococcal diseases.

Hib vaccine: Hib is a common pathogen in respiratory tract, which is mainly transmitted directly through droplets. After infection, it can not only cause non-bacteremia pneumonia, otitis media, sinusitis and conjunctivitis, but also lead to invasive diseases, mainly manifested as meningitis, pneumonia, bacteremia, cellulitis and other multi-system and multi-site infections. In 2000, Haemophilus influenzae infection caused 371,000 deaths worldwide, most of which were children under 5 years old.

According to epidemiological studies, Hib mainly invades children under 5 years old and infants, especially infants under 18 months old, and the peak incidence is concentrated in 6-12 months old. Hib vaccine is suitable for children from 2 months to 5 years old. Vaccination with this vaccine can effectively reduce pneumonia, meningitis and even death caused by Haemophilus influenzae infection in children.

It should be noted that both the pentavaccine and the quadruple vaccine contain Hip vaccine, so there is no need for repeated vaccination.

03

Multi-influenza vaccine/pneumonia vaccine /Hib vaccine

What is the difference?

Influenza vaccine: tetravalent influenza vaccine, compared with the original trivalent influenza vaccine, has one more influenza virus strain to prevent, and besides influenza A H1N1, H3N2 and BV strains of trivalent influenza vaccine, there is also one more influenza B BY strain.

The tetravalent influenza vaccine suitable for 6 -35 months old brings more comprehensive protection against influenza virus to infants in the younger age group, and two doses are required, with an interval of 4 weeks.

Pneumonia vaccine: pneumonia vaccine mainly includes two kinds: 13-valent pneumococcal polysaccharide conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine. It can prevent pneumonia and related infections caused by 13 and 23 corresponding serotypes of Streptococcus pneumoniae infection respectively.

The prevention scope of the two vaccines is different from that of the vaccinated population: 13-valent pneumonia vaccine can prevent pneumonia caused by 13 serotypes of Streptococcus pneumoniae, such as 1, 3, 7F and 9V; The range of prevention of 23-valent pneumonia vaccine is relatively wide, which can prevent pneumonia caused by 23 serotypes of Streptococcus pneumoniae. However, the 23-valent vaccine is a polysaccharide vaccine, and the immune response of children under 2 years old to polysaccharide antigen is weak, so the 23-valent vaccine can not protect them.

At present, the 13-valent pneumonia vaccine is mainly suitable for infants and children from 6 weeks to 5 years old; The 23-price pneumonia vaccine is suitable for children and adults over two years old.

Hib vaccine: Haemophilus influenzae type B conjugate vaccine There are three other conjugate vaccines at present, including acellular DTaP-Hib, adsorbed acellular DTP inactivated polio and Haemophilus influenzae type B conjugate vaccine (DTaP-IPV/Hib), and AC group meningococcal polysaccharide (conjugate)-Haemophilus influenzae type B conjugate vaccine (conjugate).

04

How long is the validity period of influenza vaccine/pneumonia vaccine /Hib vaccine?

Do I need to call every year?

The flu vaccine needs to be given every year. On the one hand, the epidemic subtype of influenza virus changes every year, and it is easy to mutate. Last year’s vaccine may not be able to resist this year’s virus subtype well.

On the other hand, the protective antibodies produced after vaccination can last for 6 ~ 8 months, and will gradually weaken over time. Only by vaccination every year can we obtain continuous immunity.

For children, pneumonia vaccine and Hib vaccines don’t need to be vaccinated every year, just complete the prescribed vaccination procedures according to the corresponding instructions.

05

Influenza vaccine/pneumonia vaccine /Hib vaccine

Is it necessary to call them all?

It is necessary. At present, these three kinds of vaccines belong to vaccines outside the national immunization program and are vaccinated voluntarily, so the vaccination rate of the population is still very low, and the population is generally susceptible. If there are no contraindications, vaccination is recommended.

06

Have been infected with influenza virus/Streptococcus pneumoniae/

Haemophilus influenzae type B, do you still need a vaccine?

You still need to be vaccinated. Because these three pathogens have different serotypes, each infection is only one of them, and it is impossible to produce protective antibodies against all serotypes after infection, and the vaccine contains a variety of common susceptible serotypes, which has a wide range of protection, so it is suggested that the corresponding vaccine should still be vaccinated after infection.

07

Can influenza vaccine/pneumonia vaccine /Hib vaccine be vaccinated at the same time?

These three vaccines are inactivated vaccines, which are out of the national immunization program, and can be vaccinated at the same time in principle.

08

When is the best time to get vaccinated,

Is it too late to call now?

Influenza vaccine does not take effect immediately after vaccination, and it takes 2-4 weeks to produce protective antibodies. Generally speaking, November-December is the high season of influenza every year, so September-October is the best vaccination time. Of course, the baby can still be vaccinated at any stage of the epidemic season, which can produce protection.

Pneumonia vaccine: The best age for 13-valent pneumonia vaccine is 6 weeks after birth, and for 23-valent pneumonia vaccine, it is 2 years old. If you need to vaccinate again, you need to wait five years.

Hib vaccine: The best age for vaccination is 2 months after birth.

09

Can you prevent pneumonia 100% after vaccination?

That’s not true. Although the vaccine can prevent most people from being infected, the protection rate cannot reach 100%, which is related to the characteristics of the vaccine itself and the personal physique of the recipient. The vaccine can only prevent specific pathogens.

10

Which children can’t get this kind of vaccine?

(1) Those who are allergic to any ingredients contained in the vaccine (including auxiliary materials, formaldehyde, cracking agents and antibiotics) are prohibited from vaccination. Egg allergy is not recommended as a taboo for influenza vaccination.

(2) Patients with mild to moderate acute diseases with or without fever symptoms should be vaccinated after the symptoms subside.

* (For details, please refer to different vaccine instructions or the special clinic for immunization consultation in the lakeside campus of Zhejiang University Children’s Hospital, Tuesday afternoon, Wednesday and Thursday morning. )

In addition, there are still some contraindications and caution in vaccination. Parents should inform the doctor of the child’s medical history, allergy history and medication history before taking their children for vaccination.

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